Table 3

Changes in blood parameters prior to, at two and six months of treatment

Variables

Groups


Zinc

Vitamin A

Zinc+ Vit A

Placebo


Plasma CRP (mg/L), median (IQR)

0 month

25.7 (13.7-38.8)

27.9 (11.5-42.1)

29.1 (12.6-43.0)

30.9 (13.3-47.4)

2 month

4.6 (1.4-13.8) ‡

4 (1-14.3)‡

4.2 (1.3-15.5) ‡

6.4 (1.5-14.6) ‡

6 month

1.3 (0.5-2.7)‡

1.5(0.6-3.3)‡

1.1 (0.5-4.4) ‡

1.7 (0.9-40)‡

Serum albumin (g/dL), mean ± SD

0 month

3.8 ± 0.84

4.0 ± 0.75

4.0 ±0.96

3.8 ± 0.83

2 month

4.5 ± 0.68‡

4.3 ± 0.88†

4.4 ± 0.74

4.4 ± 0.78‡

6 month

4.6 ± 0.52‡

4.6 ± 0.72‡

4.7 ± 0.62‡

4.6 ± 0.52‡

Leukocytes(cells/mm3),median (IQR)

0 month

9300 (7575-13000)

9750 (7775-11575)

10200 (7475-12250)

9750 (7000-2225)

2 month

6700 (5400-8100)‡

6600 (5600-8050)‡

7500 (5500-8875)‡

7300 (5900-9100)‡

6 month

6000 (5100-7000)‡

6900(5275-8100)‡

6800 (5850-7800)‡

6800(5800-8100)‡

ESR (mm),median (IQR)

0 month

73.0 (48.0-99.5)

59.5 (40.0-88.5)

62.0 (36.0-92.0)

75.0 (42.0-109.0)

2 month

28 (16-40)‡

31 (18-40)‡

30 (17.3-38.8)‡

28 (16-45)‡

6 month

11 (4-28)‡

14 (8-28.8)‡

12 (6-28)‡

11 (8-28)‡

Hemoglobin(g/dL), mean ± SD

0 month

11.2 ± 2.7

11.6 ± 2.4

11.6 ± 2.5

11.0 ± 2.5

2 month

12.5 ± 2.78‡

12.6 ± 2.55‡

13.18 ± 2.48‡

12.12 ± 2.43‡

6 month

12.8 ± 2.3‡

13.0 ± 2.2‡

13.3 ± 2.2‡

12.8 ± 2.3‡

Plasma zinc(μmol/L), mean ± SD

0 month

11.6 ± 2.2

11.9 ± 3

12.1 ± 3.0

11.8 ± 2.4

2 month

11.7 ± 2.43†

11.6 ± 1.83‡

12.5 ± 2.33‡

11.7 ± 2.33‡

6 month

13.1 ± 1.92†

12.5 ± 2.1†

12.8 ± 2.9†

12.6 ± 1.7 3‡

Plasma retinol(μmol/L), median (IQR)

0 month

0.7(0.5-1.0)

0.7(0.5-1.5)

0.7(0.4-1.1)

0.7 (0.5-1)

2 month

1.2 (1-1.6)a

1.5(1-2)ab

1.3 (1-1.9)‡

1.2 (0.9-1.6)b

6 month

1.4 (1.1-1.9)†

1.6 (1.2-2.0)‡

1.6 (1.2-1.9)

1.4 (1.0-1.8)‡


SD = standard deviation, IQR = interquartile range, *significant difference of proportion between groups (chi-squared, p < 0.05), significant changes from baseline p < 0.05† and p < 0.001‡, ab significant changes between group (One-way ANOVA, p < 0.05)

Pakasi et al. Nutrition Journal 2010 9:41   doi:10.1186/1475-2891-9-41

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