Table 3

Questionnaire scores before and after active (high cocoa liquor/polyphenol rich chocolate) and placebo (simulated iso-calorific chocolate - cocoa liquor free/low polyphenol)

Questionnaires

Before Intervention

After Intervention (8 weeks)

Wilcoxon Signed Rank Sum test


Median (Range)

Median (Range)

Z value (Exact Sig. (2-tailed))

Chalder Fatigue questionnaire Active Arm

33 (25 - 38)

21.5 (6 - 35)

-2.53 (0.01)


Chalder Fatigue questionnaire Placebo Arm

28.5 (17 - 20)

34.5 (13-26)

-2.23 (0.03)


HAD questionnaire (Anxiety) Active Arm

9.5 (8-13)

6 (4-8)

-2.54 (0.01)


HAD questionnaire (Anxiety) Placebo Arm

6 (3-9)

9 (8-12)

-2.21 (0.03)


HAD questionnaire (Depression) Active Arm

10 (9-14)

5.5 (4-9)

-2.68 (0.01)


HAD questionnaire (Depression) Placebo Arm

6 (4-9)

12 (8-14)

-2.34 (0.02)


LHS questionnaire (residual function) Active Arm

0.49 (0.33 - 0.62)

0.64 (0.44 - 0.83)

-2.52 (0.01)


LHS questionnaire (residual function) Placebo Arm

0.44 (0.43 - 0.68)

0.36 (0.33 - 0.62)

-2.21 (0.03)


Sathyapalan et al. Nutrition Journal 2010 9:55   doi:10.1186/1475-2891-9-55

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