Table 1 |
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|
Characteristics of 214 Ugandan HIV infected children analysed for vitamin B12 and folate by intervention group |
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|
Number (N) |
MMS n (%) |
'Standard of care' MV n (%) |
p-value |
|
|
|
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|
Sex: Male |
100 |
49 (49.0) |
51 (51.0) |
>0.99 |
|
Age less than 24 months |
70 |
33 (47.1) |
37 (52.9) |
0.77 |
|
Mother as carer |
146 |
73 (50.0) |
73 (50.0) |
0.56 |
|
On HAART |
44 |
19 (43.2) |
25 (56.8) |
0.50 |
|
Routine CTX |
193 |
93 (48.2) |
100 (51.8) |
0.82 |
|
Routine MV |
144 |
68 (47.2) |
76 (52.8) |
0.66 |
|
WHZ < -2 |
28 |
14 (50.0) |
14 (50.0) |
>0.99 |
|
HAZ < -2 |
113 |
56 (49.6) |
57 (50.4) |
0.89 |
|
WHO stage 3 or 4 |
56 |
26 (46.4) |
30 (53.6) |
0.76 |
|
CD4+ T cells < 25% |
114 |
50 (43.9) |
64 (56.1) |
0.20 |
|
Elevated CRP (> 6 g/dl) |
67 |
33 (49.3) |
34 (50.7) |
0.42 |
|
Low haemoglobin (< 11 g/dl) |
127 |
61 (48.0) |
66 (52.0) |
0.89 |
|
Low vitamin B12 (< 221 pmol/L) |
60 |
29 (48.3) |
31 (51.7) |
0.96 |
|
Low folate (< 13.4 nmol/L) |
62 |
25 (40.3) |
37 (59.7) |
0.13 |
|
|
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|
MMS = multiple micronutrient supplementation HAART = Highly active anti-retroviral therapy CTX = Cotrimoxazole MV = 'standard of care' multivitamins WHZ = Weight for height z-score HAZ = Height for age z-score WHO = World Health Organisation CD4+ = Cluster of differentiation 4 CRP = C-reactive protein |
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|
Ndeezi et al. Nutrition Journal 2011 10:56 doi:10.1186/1475-2891-10-56 |
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