Table 1

Hazard ratios for disease progression in breast cancer patients
All (N = 980) Events (N = 141) Model 1a Model 2b
Age (mean(SD)) 48 (9.8) 49 (11.7) 1.02 (1.00-1.04) 1.01 (0.99-1.03)
 ≤39 191 (19.5) 30 (21.3) 1.00 1.00
 40-49 422 (43.0) 50 (35.5) 0.86 (0.54-1.36) 0.76 (0.48-1.22)
 50-59 241 (24.6) 34 (24.1) 1.02 (0.62-1.70) 0.83 (0.48-1.42)
 ≥60 126 (12.9) 27 (19.1) 1.66 (0.97-2.82) 1.21 (0.67-2.18)
Menopausal status
 Pre 610 (63.0) 74 (53.6) 1.00 1.00
 Post 359 (37.0) 64 (46.4) 1.50 (0.93-2.42) 1.38 (0.85-2.25)
BMI, kg/m2 (mean(SD)) 23 (2.9) 23 (3.2) 0.98 (0.92-1.04) 0.97 (0.91-1.03)
 <25 753 (77.6) 107 (77.0) 1.00 1.00
 ≥25 217 (22.4) 32 (23.0) 0.85 (0.56-1.28) 0.79 (0.52-1.20)
Education
 Middle school 224 (22.9) 46 (32.6) 1.00 1.00
 High school 402 (41.2) 56 (39.7) 0.68 (0.45-1.05) 0.69 (0.45-1.05)
 College 351 (35.9) 39 (27.7) 0.58 (0.36-0.94) 0.58 (0.36-0.93)
Alcohol drinking
 <1/month 559 (57.5) 85 (60.7) 1.00 1.00
 1-3/month 354 (36.4) 46 (32.9) 0.83 (0.57-1.21) 0.83 (0.57-1.22)
 1+/week 59 (6.1) 9 (6.4) 1.12 (0.56-2.25) 1.09 (0.54-2.19)
Recruited sites
 SNU 511 (52.1) 73 (51.8) 1.00 1.00
 AMC 469 (47.9) 68 (48.2) 0.92 (0.65-1.30) 0.89 (0.63-1.26)
TNM stage
 I 400 (40.8) 25 (17.7) 1.00 1.00
 II 416 (42.5) 72 (51.1) 2.78 (1.74-4.44) 2.71 (1.69-4.35)
 III 164 (16.7) 44 (31.2) 4.27 (2.57-7.11) 4.17 (2.50-6.96)
Tumor size
 <2 cm 526 (54.9) 42 (29.8) 1.00 1.00
 ≥2 cm 431 (44.9) 99 (70.2) 2.57 (1.74-3.79) 2.51 (1.70-3.72)
 Tx 2 (0.2)
Lymph node status
 Negative 577 (58.9) 60 (42.6) 1.00 1.00
 Positive 390 (39.8) 78 (55.3) 1.47 (1.03-2.11) 1.46 (1.02-2.09)
 Nx 13 (1.3) 3 (2.1)
Hormone status
 ER + and/or PR+ 698 (72.6) 74 (53.6) 1.00 1.00
 ER–/PR– 264 (27.4) 64 (46.4) 2.06 (1.41-3.01) 2.06 (1.40-3.02)
Nuclear grade
 I-II 525 (55.2) 57 (41.0) 1.00 1.00
 III 426 (44.8) 82 (59.0) 1.15 (0.78-1.69) 1.12 (0.75-1.65)

Abbreviation: AMC, Asan Medical Center; ER, estrogen receptor; PR, progesterone receptor; SNU, Seoul National University.

Data are presented as frequency (percentage), except for age and BMI in continuous variable, which are expressed as mean (SD).

a Adjusted for age, TNM stage and hormone status and nuclear grade.

b Adjusted for age, education, recruited site, TNM stage, hormone status and nuclear grade.

Lee et al.

Lee et al. Nutrition Journal 2012 11:59   doi:10.1186/1475-2891-11-59

Open Data