Table 5

Concentration of neutral sterols and bile acids in dry faeces
Faecal neutral sterol concentration [mg/g dry faeces]
BG (n = 19) WG (n = 21) SG (n = 18)
Run-in Blue lupin Citrus Run-in White lupin Citrus Run-in Soya Citrus
Total NS 21.6 ± 8.1a 18.3 ± 5.3b 19.8 ± 6.6ab 22.8 ± 5.8 22.2 ± 6.3 20.8 ± 5.6 19.8 ± 5.8 18.7 ± 5.0 18.3 ± 5.4
Cholesterol 2.87 ± 1.82 2.56 ± 1.11 2.63 ± 1.67 2.54 ± 1.38 2.76 ± 1.53 2.98 ± 2.19 2.80 ± 2.30 2.19 ± 0.92 3.09 ± 1.62
Coprostanol 16.0 ± 6.5a 13.4 ± 4.6b 14.9 ± 5.5ab 16.8 ± 5.1 16.5 ± 5.7 15.3 ± 5.4 14.3 ± 5.3 14.2 ± 5.0 13.0 ± 5.0
Cholestanol 0.64 ± 0.11 0.64 ± 0.12 0.62 ± 0.15 0.56 ± 0.16 0.60 ± 0.08 0.59 ± 0.07 0.61 ± 0.10 0.61 ± 0.14 0.60 ± 0.12
Coprostanone 1.85 ± 1.32a 1.38 ± 1.00b 1.40 ± 0.81ab 2.49 ± 1.55a 1.94 ± 1.23ab 1.57 ± 0.85b 1.67 ± 0.88 1.31 ± 0.75 1.26 ± 0.62
Cholestanone 0.04 ± 0.06 0.05 ± 0.05 0.05 ± 0.06 0.14 ± 0.03 0.14 ± 0.06 0.13 ± 0.03 0.10 ± 0.03 0.11 ± 0.02 0.11 ± 0.04
Cholestenone 0.24 ± 0.14 0.20 ± 0.11 0.22 ± 0.11 0.30 ± 0.08 0.27 ± 0.07 0.30 ± 0.12 0.26 ± 0.09 0.24 ± 0.07 0.27 ± 0.11
Faecal bile acid concentration [mg/g dry faeces]
BG (n = 26) WG (n = 24) SG (n = 25)
Run-in Blue lupin Citrus Run-in White lupin Citrus Run-in Soya Citrus
Total BA 6.97 ± 2.72a 6.03 ± 2.17a 5.07 ± 1.82b 6.86 ± 1.86a 5.45 ± 1.73b 5.27 ± 1.95b 6.40 ± 2.39a 5.33 ± 2.49b 5.39 ± 2.28b
Primary BA 0.53 ± 0.27 0.66 ± 0.46 0.51 ± 0.29 0.53 ± 0.34 0.62 ± 0.61 0.42 ± 0.15 0.57 ± 0.28a 0.44 ± 0.22b 0.51 ± 0.30ab
Cholic acid 0.28 ± 0.15 0.35 ± 0.25 0.26 ± 0.15 0.28 ± 0.16 0.36 ± 0.41 0.24 ± 0.13 0.28 ± 0.12a 0.22 ± 0.11b 0.26 ± 0.17ab
Chenodeoxycholic acid 0.26 ± 0.14 0.31 ± 0.23 0.24 ± 0.16 0.25 ± 0.27 0.25 ± 0.22 0.18 ± 0.07 0.30 ± 0.18a 0.22 ± 0.13b 0.25 ± 0.14ab
Secondary BA 6.43 ± 2.68a 5.36 ± 2.17b 4.57 ± 1.69b 6.33 ± 1.77a 4.83 ± 1.84b 4.85 ± 1.91b 5.83 ± 2.26a 4.89 ± 2.37ab 4.88 ± 2.23b
Iso-lithocholic acid 1.15 ± 0.56a 0.96 ± 0.44b 0.91 ± 0.48b 0.99 ± 0.42a 0.80 ± 0.46b 0.88 ± 0.51ab 1.00 ± 0.47 1.02 ± 0.50 0.90 ± 0.55
Lithocholic acid 1.57 ± 0.79a 1.27 ± 0.69b 1.06 ± 0.53c 1.45 ± 0.51a 1.12 ± 0.36b 1.03 ± 0.37b 1.38 ± 0.58a 1.08 ± 0.51b 1.07 ± 0.47b
Iso-deoxycholic acid 1.04 ± 0.65a 0.91 ± 0.55ab 0.78 ± 0.42b 1.10 ± 0.67a 0.86 ± 0.64b 0.93 ± 0.74ab 1.13 ± 0.56 1.12 ± 0.76 1.03 ± 0.66
Deoxycholic acid 2.43 ± 1.30a 2.03 ± 0.95a 1.65 ± 0.88b 2.53 ± 1.03a 1.89 ± 0.97b 1.85 ± 0.87b 2.13 ± 1.12a 1.51 ± 1.03b 1.70 ± 1.02b
12nketodeoxycholic acid 0.23 ± 0.15a 0.20 ± 0.17ab 0.17 ± 0.09b 0.26 ± 0.24a 0.16 ± 0.06b 0.16 ± 0.06b 0.19 ± 0.07 0.16 ± 0.07 0.18 ± 0.09

Values are presented as mean ± standard deviation.

BG blue lupin group, WG white lupin group, SG soya group; blue lupin, Lupinus angustifolius cv. Boregine; white lupin, Lupinus albus cv. Typ Top; soya, Glycine max cv. Hefeng; citrus, citrus fibre Herbacel AQ Plus serving as active comparator; NS neutral sterols, BA bile acids.

a>b>cSignificant differences between mean values within each group with unequal superscript letters (P ≤ 0.05) determined by repeated measures ANOVA.

Fechner et al.

Fechner et al. Nutrition Journal 2013 12:101   doi:10.1186/1475-2891-12-101

Open Data