Table 4

Glucose metabolism parameters
NGLCD LFD
Baseline 12 months Mean change Baseline 12 months Mean change
FPG (mg/dl) 104.1 ± 27.9 96.9 ± 19.7 −7.2 ± 11.2 [−10.2, - 4.2] 103.7 ± 29.2 96.5 ± 19.1 −7.2 ± 13.1* [−10.8, -3.5]
FPI (μU/ml) 14.2 (11.5-21.8) 9.1 (6.2-16.9) −7.6 ± 11.5* [−10.7, -4.6] 12.8 (8.7-18.8) 9.15 (6.06-17.08) −5.2 ± 9.2* [−7.8, -2.6]
HOMA-IR 3.33 (2.3-5.9) 1.99 (1.45-4.04) −2.4 ± 4.1 * [−3.5, -1.3] 3.06 (1.93-5.11) 2.04 (1.3-4.4) −1.8 ± 3.9* [−2.9, -0.7]
C Peptide (ng/ml) 2.31 (2.01-2.8) 2.34 (2.08-2.9) −0.03-0.2 ** [−0.09, -0.03] 2.4 (2.07-2.97) 2.41 (2.1-3.1) −0.002 ± 0.2*** [−0.004, 0.01]
HbA1c (%) 5.7 ± 0.7 5.6 ± 0.7 −0.11 ± 0.3 * [−0.02, -0.2] 5.6 ± 0.5 5.5 ± 0.5 −0.09 ± 0.2* [−0.06, 0.05]

Values are means ± SD; for variables abnormally distributed we used median ± interquartile ranges (25th and 75th percentiles).

All p >0.05 for difference between groups at baseline and 12 months; *, p < 0.05 for mean change baseline, 12 months; **, p = 0.295; ***, p = 0.925.

NGLCD normoglucidic low-calorie diet, LFD low-fat diet, FPG fasting plasma glucose, FPI fasting plasma insulin, HOMA-IR homeostasis model assessment of insulin resistance, HbA1c glycosylated hemoglobin.

Rusu et al.

Rusu et al. Nutrition Journal 2013 12:119   doi:10.1186/1475-2891-12-119

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