Table 7

Groups of weight loss and liver function parameters in patients with LFD
Weight gain 1-5% weight loss 5-10% weight loss Weight loss >10% p
Mean SD Mean SD Mean SD Mean SD
PA (min/week) Baseline 19.5 7.1 30.5 19.0 31.2 22.2 15.0 . 0.620
12-months 33.8 11.1 71.5 36.6 70.6 34.5 85.0 . 0.229
Weight (kg) Baseline 88.9 15.4 82.8 11.0 81.2 10.5 96.0 . 0.412
12-months 90.3 15.2 80.8 11.1 75.2 10.3 84.0 . 0.090
BMI (kg/m2) Baseline 30.4 4.1 29.2 3.2 29.5 3.9 32.4 . 0.774
12-months 30.9 4.1 28.5 3.2 27.4 3.8 28.4 . 0.334
AST (IU/l) Baseline 61.5 56.2 60.0 35.3 65.1 33.0 48.0 . 0.950
12-months 63.7 57.8 50.3 31.5 55.7 31.0 36.0 . 0.811
ALT (IU/l) Baseline 63.3 43.4 74.0 44.6 73.2 39.5 69.0 . 0.972
12-months 77.1 72.9 56.0 40.3 67.8 41.0 42.0 . 0.671
Albumin (g/dl) Baseline 4.3 0.5 4.2 0.5 4.3 0.4 3.8 . 0.692
12-months 4.4 0.3 4.3 0.3 4.4 0.3 3.7 . 0.186
Bi (g/dl) Baseline 0.7 0.2 0.7 0.3 0.6 0.2 0.8 . 0.579
12-months 0.7 0.1 0.7 0.2 0.6 0.2 0.6 . 0.514
GGT (IU/l) Baseline 71.3 55.5 59.9 28.0 73.1 36.3 55.0 . 0.592
12-months 67.5 67.5 48.5 26.6 57.3 34.5 46.0 . 0.654
AST/ALT Baseline 0.9 0.2 0.9 0.3 1.0 0.4 0.7 . 0.763
12-months 0.9 0.2 1.0 0.2 0.9 0.2 0.9 . 0.424
FI Baseline 5.4 1.7 5.6 1.4 5.7 1.3 4.6 . 0.863
12-months 5.2 1.8 5.3 1.4 5.5 1.3 4.6 . 0.904
APRI Baseline 0.7 0.6 0.8 0.6 0.8 0.5 0.3 . 0.866
12-months 0.7 0.6 0.6 0.6 0.7 0.4 0.3 . 0.887

LFD low fat diet, PA physical activity, BMI body mass index, AST aspartate aminotransferase, ALT alanine aminotransferase, Bi bilirubin, GGT gamma-glutamyl transpeptidase, AST/ALT aspartate aminotransferase/alanine aminotransferase ratio, FI Forns fibrosis index, APRI AST to platelet ratio index.

Rusu et al.

Rusu et al. Nutrition Journal 2013 12:119   doi:10.1186/1475-2891-12-119

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