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Open Access Research

Metabolic syndrome risk factors in overweight, obese, and extremely obese brazilian adolescents

Anapaula CB Rizzo1, Tamara BL Goldberg2*, Carla C Silva3, Cilmery S Kurokawa4, Helio RC Nunes5 and José E Corrente6

Author affiliations

1 Department of Pediatrics, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil

2 Department of Pediatrics, Adolescent Medicine Course, Post Graduate Program in Gynecology, Obstetrics, and Mastology, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil

3 Department of Physical Education, University of North Paraná, Paraná, Brazil

4 Clinical and Experimental Pediatric Research Center, Department of Pediatrics, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil

5 Statistical Consultant, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil

6 Department of Statistics, Botucatu School of Medicine, São Paulo State University (UNESP), São Paulo, Brazil

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Citation and License

Nutrition Journal 2013, 12:19  doi:10.1186/1475-2891-12-19

Published: 30 January 2013

Abstract

Background

Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population.

Methods

A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study. Adolescents underwent anthropometric evaluation (weight, height, and abdominal circumference) and Body Mass Index (BMI) was estimated according to age and gender, following Disease Control and Prevention Centers recommendations (CDC, 2000). Blood pressure was measured and individuals with BMI ≥ 85th percentile were submitted to laboratory evaluation for Total Cholesterol, HDL and LDL Cholesterol, Triglycerides, Fasting Insulinemia, and Fasting Glycemia to identify MS factors, according to the criteria suggested by the International Diabetes Federation. Insulin resistance was calculated by HOMA-IR, Quicki, and Fasting Glycemia/Fasting Insulinemia (FGI).

Results and discussion

Of the 321 adolescents, 95 (29.6%) were overweight, 129 (40.2%) were obese, and 97 (30.2%) were extremely obese. Around 18% were diagnosed with MS. The most prevalent risk factors were abdominal circumference ≥90th percentile (55%), HDL < 40 mg/dL (35.5%), High Pressure ≥130/85 mm/Hg (21%), Triglycerides ≥150 mg/dL (18.5%), and Fasting Glycemia ≥100 mg/dL (2%). Insulin resistance was observed in 65% of the adolescents.

Conclusion

An increased prevalence of overweight and obesity, together with cardiometabolic risk factors such as dyslipidemia and abnormal blood pressure, were observed in adolescents, contributing to the onset of metabolic syndrome at younger ages. Risk factors for MS were more prevalent in females.

Keywords:
Obesity; Metabolic Syndrome; Adolescents; Risk factors; Insulin resistance