Table 2

Descriptive statistics of dietary nitrate, nitrite, and nitrosamine intake and neural tube defects in offspring
N (%)
 Outcome N Mean (SD) Quartile 1 Quartile 2 Quartile 3 Quartile 4
Nitrate (mg/day)
Anencephaly 319 48.02 (32.99) 90 (28.2) 84 (26.3) 65 (20.4) 80 (25.1)
Spina bifida 658 49.83 (43.40) 179 (27.2) 168 (25.5) 172 (26.1) 139 (21.1)
Encephalocele 127 49.75 (36.88) 35 (27.6) 28 (22.0) 37 (29.1) 27 (21.3)
Total Nitrite (mg/day)
Anencephaly 319 1.88 (0.99) 74 (23.2) 63 (19.7) 86 (27.0) 96 (30.1)
Spina bifida 662 1.85 (1.05) 157 (23.7) 153 (23.1) 165 (24.9) 187 (28.2)
Encephalocele 127 1.84 (1.04) 32 (25.2) 31 (24.4) 28 (22.0) 36 (28.3)
Animal Nitrite (mg/day)
Anencephaly 320 1.15 (0.70) 71 (22.2) 71 (22.2) 89 (27.8) 89 (27.8)
Spina bifida 673 1.14 (0.79) 157 (23.3) 166 (24.7) 180 (26.7) 170 (25.3)
Encephalocele 128 1.20 (0.89) 37 (28.9) 23 (18.0) 31 (24.2) 37 (28.9)
Plant Nitrite (mg/day)
Anencephaly 319 0.74 (0.51) 76 (23.8) 84 (26.3) 65 (20.4) 94 (29.5)
Spina bifida 666 0.72 (0.49) 170 (25.5) 162 (24.3) 138 (20.7) 196 (29.4)
Encephalocele 129 0.66 (0.37) 29 (22.5) 31 (24.0) 38 (29.5) 31 (24.0)
Nitrosamine (μg/day)
Anencephaly 315 0.53 (0.30) 77 (24.4) 77 (24.4) 84 (26.7) 77 (24.4)
Spina bifida 664 0.55 (0.34) 181 (27.3) 150 (22.6) 157 (23.6) 176 (26.5)
Encephalocele 127 0.52 (0.32) 34 (26.8) 34 (26.8) 26 (20.5) 33 (26.0)

Huber et al.

Huber et al. Nutrition Journal 2013 12:34   doi:10.1186/1475-2891-12-34

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