Open Access Research

Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial

Daniel E Roth1*, Abdullah Al Mahmud2, Rubhana Raqib2, Evana Akhtar2, Nandita Perumal1, Brendon Pezzack1 and Abdullah H Baqui23

Author Affiliations

1 Department of Paediatrics, Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada

2 International Center for Diarrhoeal Disease Research, Bangladesh (icddr, b), GPO Box 128, Dhaka 1000, Bangladesh

3 Department of International Health, The Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA

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Nutrition Journal 2013, 12:47  doi:10.1186/1475-2891-12-47

Published: 12 April 2013

Additional files

Additional file 1:

Note regarding an interim DSMB review. This note describes an interim review conducted by the data and safety monitoring board (DSMB).

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Additional file 2:

AViDD trial sensitivity analyses, weekly symptoms reported, and biochemical and safety data. This file includes summaries of intention-to-treat analyses versus sensitivity analyses (Table S1), frequency of reported symptoms based on weekly clinical monitoring (Table S2), biochemical adverse events (Table S3) and clinical serious adverse events (Table S4) at any time during follow-up, and biochemical and clinical data among newborns with clinical serious adverse events (birth to 1 month postnatal).

Format: PDF Size: 158KB Download file

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Open Data