Table 2

Mean values of all variables by VDR genotype in subjects with MetSyn
Variables VDR 2228570 C > T (Fok I) p VDR 1544410 A > G (Bsm I) p
FF Ff ff BB Bb bb
n = 130 n = 91 n = 22 n = 109 n = 102 n = 32
WC (cm) 103 (±13) 103 (±12) 106 (±13) 0.433 104 (±13) 103 (±13) 104 (±13) 0.863
Triglycerides (mg/dl) 155 (±59) 174 (±81) 163 (±103) 0.204 151 (±59) 173 (±87) 163 (±64) 0.523
BPS (mmHg) 140 (±18) 137 (±16) 147 (±24) 0.377 139 (±14) 139 (±20) 134 (±20) 0.490
BPD (mmHg) 84 (±12) 82 (±10) 85 (±12) 0.726 84 (±10) 83 (±10) 82 (±8) 0.822
Fasting glucose (mg/dl) 99 (±10) 98 (±13) 99 (±14) 0.707 100 (±12) 97 (±13) 99 (±12) 0.404
HDL cholesterol (mg/dl) 43 (±12) 40 (±9) 40 (±12) 0.306 43 (±12) 42 (±10) 40 (±12) 0.231
HOMA IR 2 (±2) 3 (±2) 4 (±3)† 0.014 3 (±1) 3 (±2) 4 (±3) 0.259
HOMA β 100 (±77) 159 (±137)‡ 145 (±61) 0.010 123 (±77) 142 (±137) 137 (±107) 0.729
25(OH)D3 (ng/ml) 24 (±6.8) 24.8 (±16.8) 24 (±8) 0.828 24 (±6.4) 62 (±8.4) 24 (±8) 0.389
iPTH (pg/dl) 37 (±19) 49 (±22)‡ 42 (±25) 0.022 44 (±15) 49 (±22) 46 (±25) 0.649

Legend:WC, Waist circumference; BPS, Systolic blood pressure; BPD, Diastolic blood pressure; HOMA IR, Insulin resistance; HOMA β, Cell function; iPTH, Intact parathyroid hormone; 25(OH)D3, Vitamin D. Data are expressed as mean (Standard Deviation). P values were calculated using ANOVA followed by Bonferroni test and adjusted for age. † significant for the heterozygous genotype; ‡ significant for the normal dominant homozygous genotype.

Schuch et al.

Schuch et al. Nutrition Journal 2013 12:96   doi:10.1186/1475-2891-12-96

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