Table 3

Comparison of 5-hour area under the curve (AUC0-5 h) responses of biomarkers to test meals1
Biomarkers Control (n = 16) Walnut (n = 16)
LS Mean 95% CI LS Mean 95% CI P value
Total polyphenols, mmol GAE/L × h 6.96 5.87, 8.25 7.39 5.87, 9.39 0.076
Malondialdehyde, μmol/L × h 0.81 0.62, 1.01 0.75 0.63, 0.87 0.048
ORAC(hydrophilic), mmol/L × h 7.14 6.53, 7.76 7.68 7.10, 8.26 0.008
ORAC(lipophilic), mmol/L × h 3.80 3.43, 4.17 4.12 3.80, 4.45 0.000
FRAP, mmol Trolox equivalents/L 6.57 5.46, 7.69 6.47 5.37,7.58 0.920
Uric acid, μmol/L × h 1612 1317, 1869 1651 1317, 1943 0.591
Total cholesterol, , mmol/L × h 24.1 21.4, 26.6 23.8 21.1, 26.4 0.556
Triglycerides, , mmol/L × h 12.8 9.2, 17.2 14.5 10.6, 19.1 0.037
Oxidized LDL, mmol/L × h -0.57 0.34, 0.97 -0.65 0.36, 1.16 0.910

1Values are least square means ± SEM; AUC0-5h is the area under the concentration-time curve over 5 hours estimated by using the linear trapezoidal rule. A mixed model approach was used to compare AUC0-5h among test meals adjusting for period effect and treating subjects nested within a sequence as random effects.

Haddad et al.

Haddad et al. Nutrition Journal 2014 13:4   doi:10.1186/1475-2891-13-4

Open Data