Table 1

Characteristics of the 10 trials (11 data points) included in the meta-analysis of the effects of fenugreek seeds on glycemia
Lead author, year and country Population, medication Design Age, y Male (%) Sample size, N Duration, days Fenugreek, preparation Daily dose, g Control Outcomes Study quality
RCT Blinding Dropout
Bordia et al., 1997 [42], India Mild T2DM, NR PL NR NR 40 30 Capsule, PS 5 Placebo FBG, 2 hr glucose NR NR NR
Bordia et al., 1997 [42], India Severe T2DM, NR PL NR NR 40 30 Capsule, PS 5 Placebo FBG, 2 hr glucose NR NR NR
Chevassus et al., 2010 [43], France Overweight, NR PL 38.0 100 40 42 Capsule, H 1.176 Placebo FBG, FSI Yes DB 5%
Gupta et al., 2001 [23], India T2DM, SU, BI PL 51.0 76 25 56 Capsule, H 1 Placebo FBG, 2 hr glucose, HbA1c, FSI Yes DB 4%
Lu et al., 2008 [9], China T2DM, SU PL 54.4 55 69 84 Capsule, PS 6.3 Placebo FBG, 2 hr glucose, HbA1c Yes DB NR
Alamdari et al., 2009 [17], Iran T2DM, Diet, OAD CO 43.1 100 12 56 PS 8 Unspecified FBG, 2 hr glucose, HbA1c Yes NR 25%
Chevassus et al., 2009 [25], France Healthy, NR CO 22.0 100 12 14 Capsule, H 1.176 Placebo FBG, FSI Yes DB 0%
Raghuram et al., 1994 [7], India T2DM, BI CO 46.6 NR 10 15 Chapatia, PS 25 Chapati FBG, 1 hr glucose, HbA1c Yes NR NR
Sharma et al., 1990 [44], India T1DM, Insulin therapy CO 22.7 70 10 10 Chapatia, DPS 100 Chapati FBG, 2 hr glucose, FSI Yes NR NR
Sharma et al., 1990 [22], India T2DM, BI/metformin CO 46.0 67 15 10 Chapatia, DPS 100 Chapati FBG, 2 hr glucose, FSI Yes NR NR
Sharma et al., 1990 [22], India T2DM, NR CO 42.0 NR 5 20 Chapatia, DPS 100 Chapati FBG, 2 hr glucose Yes NR NR

Abbreviations: NR not reported, T1DM type 1 diabetes mellitus, T2DM type 2 diabetes mellitus, SU sulfonylurea, BI biguanides, OAD oral antidiabetic drug, PL parallel, CO crossover trials, Daily dose, g fenugreek total daily dose in grams, PS powdered fenugreek seeds, H Hydro-alcoholic extract of fenugreek seeds, DPS Debitterized fenugreek seed powder, FBG fasting blood glucose, HbA1c % glycosylated hemoglobin, FSI fasting serum insulin, RCT randomized control trial, DB double blinded, aFenugreek incorporated into chapati (unleavened bread).

Neelakantan et al.

Neelakantan et al. Nutrition Journal 2014 13:7   doi:10.1186/1475-2891-13-7

Open Data