Table 3

Effects of isoflavones on serum LDL-cholesterol, HDL-cholesterol and triglycerides levels. Isoflavones in the forms of tablets or isolated soy protein (ISP) did not show significant benefits over serum LDL-cholesterol, HDL-cholesterol and triglycerides levels. The results were not heterogeneous to combine.

Type of intervention*
No. of trials
No. of comparisons
No. of subjects
Treatment effect (mmol/L) †
Heterogeneity p-value

1.) Isoflavones tablets





     LDL
9
11[8,10,12,13,16-18,20,21]
446
0.00 (-0.14, 0.15)
0.94
     HDL
10
12[8-10,12,13,16-18,20,21]
482
0.01 (-0.05, 0.06)
0.98
     TG
9
12[8-10,12,13,16,17,20,21]
482
0.03 (-0.06, 0.12)
0.93
2.) ISP (+)





     LDL
3
5 [14,15,23]
173
-0.06 (-0.16, 0.03)
0.84
     HDL
3
5 [14,15,23]
173
-0.01 (-0.07, 0.05)
0.97
     TG
3
5 [14,15,23]
173
0.02 (-0.05, 0.09)
1.00

* 'ISP (+)' = isoflavones containing isolated soy protein; 'LDL' = Low density lipoprotein cholesterol; 'HDL' = High density lipoprotein cholesterol; 'TG' = Triglycerides † 95% confidence interval in parenthesis

Yeung and Yu Nutrition Journal 2003 2:15   doi:10.1186/1475-2891-2-15

Open Data