Table 2

List of some important drugs under clinical trials for weight reduction.

Drugs in phase II trials

Drugs in phase III trials

Bupropion (dopamine reuptake inhibitor)

Mazindol (adrenergic agonist)

Linitript (cholecystokinin A antagonist)

Sertraline (selective serotonin uptake inhibitor)

Pegylated leptin

Posatirelin (thyrotrphin-releasing hormone analogue)

Dipeptidyl peptidase IV inhibitors

Cannabinoid antagonists

Human growth hormone factor AOD9604

Lipase inhibitor, ATL-962

Phytostanol

Nammi et al. Nutrition Journal 2004 3:3   doi:10.1186/1475-2891-3-3