Table 1

Homocysteine lowering intervention trials for the prevention of CVD.

1. SEARCH: Study of the effectiveness of additional reduction in cholesterol and homocysteine. University of Oxford, England.

2. PACIFIC: Prevention with a combined inhibitor of folate in coronary heart disease. University of Sydney, Australia.

3. WACS: Women's antioxidant and cardiovascular disease study. Harvard Medical School, USA.

4. CHAOS-2: Cambridge heart antioxidant study. University of Cambridge, England.

5. NORVITE: Norwegian study of homocysteine lowering with B-vitamins in myocardial infarction. University of Tromso, Norway.

6. BERGEN: Bergen vitamin study. University of Bergen, Norway.

7. HOPE-2: Health outcome and prevention evaluation number 2. Canada.

8. VISP: Vitamin intervention for stroke prevention. Wake Forest University, USA.

9. VITATOPS: Vitamins to prevent strokes. Perth, Australia.

10. IST-2: International strokes trial number 2. Auckland, New Zealand.

Hayden and Tyagi Nutrition Journal 2004 3:4   doi:10.1186/1475-2891-3-4