Table 1

Homocysteine lowering intervention trials for the prevention of CVD.

1. SEARCH: Study of the effectiveness of additional reduction in cholesterol and homocysteine. University of Oxford, England.
2. PACIFIC: Prevention with a combined inhibitor of folate in coronary heart disease. University of Sydney, Australia.
3. WACS: Women's antioxidant and cardiovascular disease study. Harvard Medical School, USA.
4. CHAOS-2: Cambridge heart antioxidant study. University of Cambridge, England.
5. NORVITE: Norwegian study of homocysteine lowering with B-vitamins in myocardial infarction. University of Tromso, Norway.
6. BERGEN: Bergen vitamin study. University of Bergen, Norway.
7. HOPE-2: Health outcome and prevention evaluation number 2. Canada.
8. VISP: Vitamin intervention for stroke prevention. Wake Forest University, USA.
9. VITATOPS: Vitamins to prevent strokes. Perth, Australia.
10. IST-2: International strokes trial number 2. Auckland, New Zealand.

Hayden and Tyagi Nutrition Journal 2004 3:4   doi:10.1186/1475-2891-3-4

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