Table 4

Antioxidant parameters in healthy volunteers after regular consumption of native or dealcoholized red wine

RW
 DRW
 Controls
Subjects, n
 24
 25
 25
Parameter


TPP, mg CE/L


     Baseline
 15.6 ± 1.6
 15.6 ± 2.1
 15.5 ± 1.4
     6 wk
 16.4 ± 1.4*
 16.0 ± 2.0
 15.3 ± 2.2
TEAC, mmol/L


     Baseline
 1.47 ± 0.06
 1.44 ± 0.08
 1.46 ± 0.08
     6 wk
 1.45 ± 0.04
 1.42 ± 0.07
 1.43 ± 0.07
Vitamin C, mg/dL


     Baseline
 1.30 ± 0.28
 1.43 ± 0.36
 1.48 ± 0.29
     6 wk
 1.35 ± 0.26
 1.42 ± 0.39
 1.57 ± 0.28
α-Tocopherol, mg/dL


     Baseline
 11.3 ± 3.0
 11.2 ± 2.6
 11.2 ± 2.9
     6 wk
 11.3 ± 3.0
 11.5 ± 2.7
 11.0 ± 2.7
Uric acid, mg/dL


     Baseline
 4.7 ± 1.2
 4.4 ± 1.1
 4.4 ± 1.2
     6 wk
 4.9 ± 1.2
 4.5 ± 0.9
 4.7 ± 1.5*
Albumin, g/dL


     Baseline
 4.2 ± 0.4
 4.3 ± 0.4
 4.2 ± 0.4
     6 wk
 4.3 ± 0.4
 4.1 ± 0.6
 4.2 ± 0.5
Bilirubin, mg/dL


     Baseline
 0.68 ± 0.28
 0.68 ± 0.33
 0.64 ± 0.33
     6 wk
 0.61 ± 0.35
 0.59 ± 0.27*
 0.62 ± 0.35
TM0, arbitrary units


     Baseline
 2,18 ± 0,56
 1,97 ± 0,56
 2,22 ± 0,79
     6 wk
 1,88 ± 0,48*
 2,05 ± 0,70
 1,95 ± 0,49
TM300, arbitrary units


     Baseline
 1,02 ± 0,69
 0,87 ± 0,72
 0,95 ± 0,54
     6 wk
 0,96 ± 0,49
 0,92 ± 0,65
 1,18 ± 0,50

Amounts ingested daily for 6 weeks were 200 mL red wine (RW) or 175 mL dealcoholized red wine (DRW). Control subjects did not receive any study drink.

TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks);

TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks)

Values are means ± SD

*Values different from baseline, P < 0.05 by Wilcoxon signed rank test

Arendt et al. Nutrition Journal 2005 4:33   doi:10.1186/1475-2891-4-33