Table 4

Antioxidant parameters in healthy volunteers after regular consumption of native or dealcoholized red wine

RW

DRW

Controls


Subjects, n

24

25

25


Parameter

TPP, mg CE/L

Baseline

15.6 ± 1.6

15.6 ± 2.1

15.5 ± 1.4

6 wk

16.4 ± 1.4*

16.0 ± 2.0

15.3 ± 2.2

TEAC, mmol/L

Baseline

1.47 ± 0.06

1.44 ± 0.08

1.46 ± 0.08

6 wk

1.45 ± 0.04

1.42 ± 0.07

1.43 ± 0.07

Vitamin C, mg/dL

Baseline

1.30 ± 0.28

1.43 ± 0.36

1.48 ± 0.29

6 wk

1.35 ± 0.26

1.42 ± 0.39

1.57 ± 0.28

α-Tocopherol, mg/dL

Baseline

11.3 ± 3.0

11.2 ± 2.6

11.2 ± 2.9

6 wk

11.3 ± 3.0

11.5 ± 2.7

11.0 ± 2.7

Uric acid, mg/dL

Baseline

4.7 ± 1.2

4.4 ± 1.1

4.4 ± 1.2

6 wk

4.9 ± 1.2

4.5 ± 0.9

4.7 ± 1.5*

Albumin, g/dL

Baseline

4.2 ± 0.4

4.3 ± 0.4

4.2 ± 0.4

6 wk

4.3 ± 0.4

4.1 ± 0.6

4.2 ± 0.5

Bilirubin, mg/dL

Baseline

0.68 ± 0.28

0.68 ± 0.33

0.64 ± 0.33

6 wk

0.61 ± 0.35

0.59 ± 0.27*

0.62 ± 0.35

TM0, arbitrary units

Baseline

2,18 ± 0,56

1,97 ± 0,56

2,22 ± 0,79

6 wk

1,88 ± 0,48*

2,05 ± 0,70

1,95 ± 0,49

TM300, arbitrary units

Baseline

1,02 ± 0,69

0,87 ± 0,72

0,95 ± 0,54

6 wk

0,96 ± 0,49

0,92 ± 0,65

1,18 ± 0,50


Amounts ingested daily for 6 weeks were 200 mL red wine (RW) or 175 mL dealcoholized red wine (DRW). Control subjects did not receive any study drink.

TPP: total phenolic content in plasma; CE: catechin equivalents; TEAC: trolox equivalent antioxidant capacity; TM0: Tail Moment in untreated cells (endogenous DNA strand breaks);

TM300: Tail Moment in cells treated with 300 μM H2O2 for 20 min (exogenous DNA strand breaks)

Values are means ± SD

*Values different from baseline, P < 0.05 by Wilcoxon signed rank test

Arendt et al. Nutrition Journal 2005 4:33   doi:10.1186/1475-2891-4-33

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