Table 6

Nuclear receptor and COX-2 mRNA expression in colorectal tumors of patients with BMI ≥ 25

Gene

n

Healthy colon mucosa

Tumor tissue

pa



Median

Range

Median

Range


PPARγ

11

0.95

(0.35–2.11)

0.97

(0.28–4.71)

n.s.

PPARδ

11

1.28

(0.72–2.00)

1.52

(0.40–4.49)

0.022

RXRα

11

0.64

(0.20–1.25)

0.85

(0.21–3.49)

0.047

RARα

11

1.17

(0.72–1.88)

1.44

(0.38–3.72)

0.018

RARβ

11

1.30

(0.12–5.39)

2.12

(0.24–10.82)

0.014

RARγ

11

1.60

(0.49–9.52)

3.17

(0.83–15.80)

<0.001

COX-2

11

2.93

(0.44–6.75)

13.20

(0.85–166.86)

<0.001


Delage et al. Nutrition Journal 2007 6:20   doi:10.1186/1475-2891-6-20

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