Table 6

Nuclear receptor and COX-2 mRNA expression in colorectal tumors of patients with BMI ≥ 25

Gene
n
Healthy colon mucosa
Tumor tissue
pa







Median
Range
Median
Range


PPARγ
11
0.95
(0.35–2.11)
0.97
(0.28–4.71)
n.s.
PPARδ
11
1.28
(0.72–2.00)
1.52
(0.40–4.49)
0.022
RXRα
11
0.64
(0.20–1.25)
0.85
(0.21–3.49)
0.047
RARα
11
1.17
(0.72–1.88)
1.44
(0.38–3.72)
0.018
RARβ
11
1.30
(0.12–5.39)
2.12
(0.24–10.82)
0.014
RARγ
11
1.60
(0.49–9.52)
3.17
(0.83–15.80)
<0.001
COX-2
11
2.93
(0.44–6.75)
13.20
(0.85–166.86)
<0.001

Delage et al. Nutrition Journal 2007 6:20   doi:10.1186/1475-2891-6-20