Table 2 |
||||
|
WOMAC Index scores during the study period in 16 evaluable subjects |
||||
| Study groups and time points |
WOMAC Index scores, mean (SD) |
|||
|
|
||||
| Pain |
Stiffness |
Physical function |
Total symptoms |
|
|
|
||||
| Hyal-Joint® (n = 8) |
||||
| Baseline |
10.4 (3.6) |
4.2 (1.0) |
36.3 (7.7) |
50.9 (12.0) |
| Week 4 |
8.8 (3.4) |
3.9 (1.6) |
28.1 (9.2) |
40.8 (13.6) |
| Week 8 |
6.3 (4.0) |
2.9 (1.9) |
23.1 (15.1) |
32.3 (20.8) |
| Change baseline vs week 4 |
-1.6 (2.7) |
-0.4 (1.5) |
-8.1 (6.3) |
-10.1 (9.6) |
| P value |
0.135 |
0.504 |
0.008 |
0.020 |
| Change baseline vs week 8 |
-4.1 (3.4) |
-1.4 (2.0) |
-13.1 (12.0) |
-18.6 (16.8) |
| P value |
0.012 |
0.092 |
0.018 |
0.016 |
| Placebo (n = 8) |
||||
| Baseline |
10.4 (2.7) |
4.5 (1.9) |
37.4 (10.6) |
52.3 (13.6) |
| Week 4 |
8.3 (3.0) |
3.5 (1.9) |
30.4 (10.7) |
42.1 (17.7) |
| Week 8 |
6.4 (2.7) |
2.9 (1.0) |
27.3 (10.7) |
36.5 (13.7) |
| Change baseline vs week 4 |
-2.1 (3.3) |
-1.0 (2.1) |
-7.0 (10.8) |
-10.1 (15.3) |
| P value |
0.113 |
0.227 |
0.110 |
0.103 |
| Change baseline vs week 8 |
-4.0 (2.8) |
-1.6 (0.9) |
-10.1 (8.6) |
-15.8 (11.4) |
| P value |
0.005 |
0.002 |
0.012 |
0.006 |
|
|
||||
|
Kalman et al. Nutrition Journal 2008 7:3 doi:10.1186/1475-2891-7-3 |
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