Table 1

Effect of germinated brown rice on AOM-induced ACF formation in male Sprague Dawley rats

No. of ACF containing


Treatment

ACF/colon

1 crypt

2 crypts

3 crypts

4 or more crypts

Total aberrant crypt


AOM + basal diet

(G1)

41.50

± 3.008

16.00

± 0.730

15.67

± 1.520

4.00

± 0.894

5.50

± 1.310

81.30

± 7.745

AOM + basal diet + 2.5 g/kg of GBR

(G2)

28.60

± 1.720a

12.20

± 1.241

10.60

± 1.208a

2.20

± 0.200

3.40

± 0.678

53.60

± 3.970a

AOM + basal diet + 5 g/kg of GBR

(G3)

25.50

± 2.327a

12.00

± 2.160

9.50

± 0.646a

2.75

± 0.250

1.25

± 0.479a

44.25

± 2.750a

AOM + basal diet +10 g/kg of GBR

(G4)

24.40

± 1.806a

10.40

± 1.123a

8.40

± 0.927a

2.20

± 0.374

2.80

± 0.860

44.00

± 4.159a

Basal diet alone (G5)

0

0

0

0

0

0


Values are expressed as mean ± SEM. Mean with the a superscript are significant p < 0.05 as compared to positive control, G1

Latifah et al. Nutrition Journal 2010 9:16   doi:10.1186/1475-2891-9-16

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