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Open Access Highly Accessed Review

Vitamin D in health and disease: Current perspectives

Ran Zhang1 and Declan P Naughton2*

Author Affiliations

1 AllergyMatters Ltd, 5a Kingston House Estate, Portsmouth Rd., Long Ditton Surrey, England KT6 5QG, UK

2 School of Life Sciences, Kingston University, Penrhyn Road, Kingston upon Thames, London KT1 2EE, UK

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Nutrition Journal 2010, 9:65  doi:10.1186/1475-2891-9-65

Published: 8 December 2010

Abstract

Despite the numerous reports of the association of vitamin D with a spectrum of development, disease treatment and health maintenance, vitamin D deficiency is common. Originating in part from the diet but with a key source resulting from transformation by exposure to sunshine, a great deal of the population suffers from vitamin D deficiency especially during winter months. It is linked to the treatment and pathogenesis and/or progression of several disorders including cancer, hypertension, multiple sclerosis, rheumatoid arthritis, osteoporosis, muscle weakness and diabetes. This widespread deficiency of Vitamin D merits consideration of widespread policies including increasing awareness among the public and healthcare professionals.